BDBM50004052 CHEMBL2180003

SMILES CC(C)(C)c1nnc2c(cc(cn12)-c1ccc(O)cc1)C(=O)NCCCc1nc2ccccc2[nH]1

InChI Key InChIKey=AZXSPZIXFIUEIE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004052   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50004052(CHEMBL2180003)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of PDE10A using [3H]cAMP and [3H]cGMP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL