BDBM50003993 CHEMBL2180011

SMILES COc1cn(nc(-c2ccnn2-c2cccc(Cl)c2)c1=O)-c1ccc(cc1F)-n1cccn1

InChI Key InChIKey=VXQLWZYFOZUKMA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003993   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50003993(CHEMBL2180011)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of human full length PDE10A expressed in SF21 cells using [3H]cGMP as substrate after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
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