BDBM50003992 CHEMBL2180803

SMILES C1CN(CCO1)c1nccnc1Oc1ccc(Nc2nc3ccccc3[nH]2)cc1

InChI Key InChIKey=AYQCPWIILRLNBK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003992   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

Curated by ChEMBL

LigandBDBM50003992(CHEMBL2180803)Copy SMILESCopy InChI

Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by IMAP TR-FR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

Curated by ChEMBL

LigandBDBM50003992(CHEMBL2180803)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL