BDBM50003560 4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene::4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2,4,6-triene::CHEMBL22207::Dextromethorphan::Levomethorpan

SMILES COc1ccc2CC3C4CCCCC4(CCN3C)c2c1

InChI Key InChIKey=MKXZASYAUGDDCJ-UHFFFAOYSA-N

Data  12 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50003560   

TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataIC50: 3.00E+5nMAssay Description:Binding of [3H]saxitoxin (STX) to rat brain sodium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2018
Entry Details Article
PubMed
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataIC50: 1.30E+3nMAssay Description:Binding of [3H]batrachotoxin (BTX) to rat brain sodium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2018
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  11.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  35.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetNorepinephrine transporter(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  179nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetKappa-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  225nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetNorepinephrine transporter(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  249nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Medical College of Georgia

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  521nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2012
Entry Details
PubMed
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  768nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  1.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetKappa-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi:  7.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50003560(Levomethorpan | CHEMBL22207 | Dextromethorphan | 4...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed