BDBM50003369 1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine::1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine; oxalic acid::1-methyl-5-(4-propoxy-1,2,5-thiadiazol-3-yl)-1,2,3,6-tetrahydropyridine::CHEMBL303922::CHEMBL308803

SMILES CCCOc1nsnc1C1=CCCN(C)C1

InChI Key InChIKey=VGRPVZDIAOGCMM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50003369   

TargetMuscarinic acetylcholine receptor M1(Rat)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 18nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 1.60nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 18nMAssay Description:In vitro binding affinity against rat hippocampus Muscarinic acetylcholine receptor M1 using [3H]pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 18nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetMuscarinic acetylcholine receptor M1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 52nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 1.60nMAssay Description:In vitro binding affinity against rat hippocampus Muscarinic acetylcholine receptor M1 using [3H]oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Novo Nordisk Cns Division

Curated by ChEMBL
LigandPNGBDBM50003369(CHEMBL308803 | CHEMBL303922 | 1-Methyl-5-(4-propox...)
Affinity DataIC50: 18nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article