BDBM50003266 (E)-3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid::3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid::CHEMBL289543

SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1Cl

InChI Key InChIKey=SNEASOMYEIJPCK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003266   

TargetType-1 angiotensin II receptor B(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003266(CHEMBL289543 | 3-[2-Butyl-3-(2-chloro-benzyl)-3H-i...)
Affinity DataIC50: 440nMAssay Description:Compound was evaluated for the inhibition of Angiotensin II receptor induced vasoconstriction of the rabbit aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003266(CHEMBL289543 | 3-[2-Butyl-3-(2-chloro-benzyl)-3H-i...)
Affinity DataIC50: 440nMAssay Description:In vitro inhibition of [125I]AII specific binding towards angiotensin II receptor in rat mesenteric membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50003266(CHEMBL289543 | 3-[2-Butyl-3-(2-chloro-benzyl)-3H-i...)
Affinity DataIC50: 4.53E+3nMAssay Description:Tested for binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50003266(CHEMBL289543 | 3-[2-Butyl-3-(2-chloro-benzyl)-3H-i...)
Affinity DataIC50: 440nMAssay Description:Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteriesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2019
Entry Details Article
PubMed