BDBM50003186 CHEMBL327710::[1-(4-Cyclohexylmethyl-3-hydroxy-2,6,10-trioxo-1-oxa-5,11-diaza-cyclotetradec-7-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)NCCCOC(=O)[C@H](O)[C@H](CC2CCCCC2)NC1=O

InChI Key InChIKey=KFDITVSMQWLPBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003186   

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003186(CHEMBL327710 | [1-(4-Cyclohexylmethyl-3-hydroxy-2,...)
Affinity DataIC50: 7.00E+3nMpH: 7.4Assay Description:The compound was evaluated in vitro for inhibition of human plasma renin at pH 7.4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003186(CHEMBL327710 | [1-(4-Cyclohexylmethyl-3-hydroxy-2,...)
Affinity DataIC50: 610nMpH: 7.4Assay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed