BDBM50003169 CHEMBL4066436

SMILES Clc1cccc(c1)C(=O)NCC1NCCc2ccccc12

InChI Key InChIKey=NQTWLZVDCRVFCR-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003169   

TargetDelta-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50003169(CHEMBL4066436)
Affinity DataIC50: 170nMAssay Description:Agonist activity at human DOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50003169(CHEMBL4066436)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells co-expressing Galpha 15 assessed as increase in intracellular calcium release incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50003169(CHEMBL4066436)
Affinity DataIC50: 1.12E+3nMAssay Description:Agonist activity at human KOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50003169(CHEMBL4066436)
Affinity DataIC50: 2.03E+3nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details Article
PubMed