BDBM50003027 (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-ol::5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-ol::CHEMBL17470

SMILES CC(C)CCCC(C)CCCC(C)N1CC[C@H]2[C@H](C)[C@@H](O)CC[C@]2(C)C1

InChI Key InChIKey=YSACNAXEZHCMEQ-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50003027   

TargetLanosterol synthase(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetDelta(14)-sterol reductase(Maize)
Institut De Botanique

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Zea mays (maize) microsomal delta 8,14-steroid 14-reductase using delta 8,14-cholestadienol as substrate after 90 min by GC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSterol-8,7-isomerase(Maize)
Institut De Botanique

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Zea mays (maize) delta8,delta7-sterol isomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetCycloeucalenol cycloisomerase(Maize)
Institut De Botanique

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Zea mays (maize) cycloeucalenol-obtusifolial isomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetC-8 sterol isomerase ERG2(Baker's yeast)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataKi:  0.400nMAssay Description:Affinity for ERG2 of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataKi:  0.5nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50003027(CHEMBL17470 | (4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5...)
Affinity DataKi:  0.600nMAssay Description:Affinity for human EMP expressed in ERG2 deficient strain of Saccharomyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed