BDBM50002472 5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanoic acid::CHEMBL288142

SMILES NCCCC(NC(=O)c1ccc(NCc2ccc3nc(N)[nH]c(=O)c3c2Cl)cc1)C(O)=O

InChI Key InChIKey=FOBMKXTWIQBNJC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002472   

TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(CHEMBL288142 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  8.30nMAssay Description:Inhibitory activity against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(CHEMBL288142 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  8.30nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(CHEMBL288142 | 5-Amino-2-{4-[(2-amino-5-chloro-4-o...)
Affinity DataKi:  8.30E+3nMAssay Description:Compound was evaluated for its binding affinity against hog liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed