BDBM50002362 CHEMBL3233630

SMILES O=C(Nc1ccc(cc1)N1CCOCC1)n1sc2ccccc2c1=O

InChI Key InChIKey=QZFUTELGYWUBNF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002362   

TargetCaspase-3(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50002362(CHEMBL3233630)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant caspase-3 using Ac-LDEVD-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetCaspase-7(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50002362(CHEMBL3233630)
Affinity DataIC50: 909nMAssay Description:Inhibition of human recombinant caspase-7 using Ac-DEVD-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetCaspase-3(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50002362(CHEMBL3233630)
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant human caspase-3 activity using Ac-DEVD-AMC as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetCaspase-7(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50002362(CHEMBL3233630)
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant human caspase-7 activity using Ac-DEVD-AMC as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed