BDBM50002198 1-(4-Fluoro-phenyl)-2-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-ethanone::CHEMBL337337

SMILES Fc1ccc(CCN2CCC(CC(=O)c3ccc(F)cc3)CC2)cc1

InChI Key InChIKey=LDOQDGKJZFBHAG-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50002198   

TargetD(2) dopamine receptor(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002198(CHEMBL337337 | 1-(4-Fluoro-phenyl)-2-{1-[2-(4-fluo...)
Affinity DataIC50: 57nMAssay Description:The compound was tested in vitro for its binding affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002198(CHEMBL337337 | 1-(4-Fluoro-phenyl)-2-{1-[2-(4-fluo...)
Affinity DataKi:  7nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002198(CHEMBL337337 | 1-(4-Fluoro-phenyl)-2-{1-[2-(4-fluo...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed