BDBM50002035 (2-Hydroxycarbamoyl-3-phenyl-propionylamino)-acetic acid::(R,S)(2-Hydroxycarbamoyl-3-phenyl-propionylamino)-acetic acid::CHEMBL17107

SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCC(O)=O

InChI Key InChIKey=GVBPRTLYHQOKRI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002035   

TargetNeprilysin(Rabbit)
Ua 498 Cnrs

Curated by ChEMBL
LigandPNGBDBM50002035(CHEMBL17107 | (2-Hydroxycarbamoyl-3-phenyl-propion...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]Ala2-Leu-enkephalin binding to Neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50002035(CHEMBL17107 | (2-Hydroxycarbamoyl-3-phenyl-propion...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50002035(CHEMBL17107 | (2-Hydroxycarbamoyl-3-phenyl-propion...)
Affinity DataIC50: 12nMAssay Description:50% inhibitory activity against enkephalinase purified from rat kidney with [3H]D-Ala2-Leu-enkephalin (20 nM) as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002035(CHEMBL17107 | (2-Hydroxycarbamoyl-3-phenyl-propion...)
Affinity DataIC50: 15nMAssay Description:Inhibitory potency against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed