BDBM50001806 1-(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL422130

SMILES Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12

InChI Key InChIKey=IXWMONQJSSRIPH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001806   

TargetAlpha-1A adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001806(CHEMBL422130 | 1-(2-{4-[6-Chloro-3-(4-fluoro-pheny...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001806(CHEMBL422130 | 1-(2-{4-[6-Chloro-3-(4-fluoro-pheny...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001806(CHEMBL422130 | 1-(2-{4-[6-Chloro-3-(4-fluoro-pheny...)
Affinity DataIC50: 37nMAssay Description:Binding affinity at dopamine D2 receptor by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001806(CHEMBL422130 | 1-(2-{4-[6-Chloro-3-(4-fluoro-pheny...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed