BDBM50001803 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144767

SMILES Cc1ccc2n(cc(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1

InChI Key InChIKey=LZSPHUKWGNMGSE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001803   

TargetAlpha-1A adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001803(CHEMBL144767 | 1-(2-{4-[3-(4-Fluoro-phenyl)-5-meth...)
Affinity DataIC50: 71nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001803(CHEMBL144767 | 1-(2-{4-[3-(4-Fluoro-phenyl)-5-meth...)
Affinity DataIC50: 920nMAssay Description:Displacement of [3H]spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001803(CHEMBL144767 | 1-(2-{4-[3-(4-Fluoro-phenyl)-5-meth...)
Affinity DataIC50: 920nMAssay Description:Binding affinity at dopamine D2 receptor by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001803(CHEMBL144767 | 1-(2-{4-[3-(4-Fluoro-phenyl)-5-meth...)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed