BDBM50001800 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-dimethyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL343444

SMILES Cc1c(-c2ccc(F)cc2)c2cc(C)ccc2n1C1CCN(CCN2CCNC2=O)CC1

InChI Key InChIKey=OUEICZGYFSHCOY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50001800   

TargetAlpha-1A adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001800(CHEMBL343444 | 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-di...)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001800(CHEMBL343444 | 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-di...)
Affinity DataIC50: 6.90E+3nMAssay Description:Displacement of [3H]spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001800(CHEMBL343444 | 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-di...)
Affinity DataIC50: 6.90E+3nMAssay Description:Binding affinity at dopamine D2 receptor by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001800(CHEMBL343444 | 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-di...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001800(CHEMBL343444 | 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-di...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]-Ketanserin from rat cortical membrane 5-HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed