BDBM50001798 1-{2-[4-(6-Chloro-1-phenyl-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-3-isopropyl-imidazolidin-2-one::CHEMBL145763

SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3)c3cc(Cl)ccc23)C1=O

InChI Key InChIKey=DRSRXSCHUHUFBD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001798   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001798(CHEMBL145763 | 1-{2-[4-(6-Chloro-1-phenyl-1H-indol...)
Affinity DataIC50: 290nMAssay Description:Compound was tested for the displacement of [3H]spiperone from Dopamine receptor D2 from rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001798(CHEMBL145763 | 1-{2-[4-(6-Chloro-1-phenyl-1H-indol...)
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001798(CHEMBL145763 | 1-{2-[4-(6-Chloro-1-phenyl-1H-indol...)
Affinity DataIC50: 39nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed