BDBM50001796 1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144086

SMILES Cc1ccc2c(cn(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1

InChI Key InChIKey=HTLQTFJVKLZPQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001796   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001796(CHEMBL144086 | 1-(2-{4-[1-(4-Fluoro-phenyl)-6-meth...)
Affinity DataIC50: 270nMAssay Description:Compound was tested for the displacement of [3H]spiperone from Dopamine receptor D2 from rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001796(CHEMBL144086 | 1-(2-{4-[1-(4-Fluoro-phenyl)-6-meth...)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001796(CHEMBL144086 | 1-(2-{4-[1-(4-Fluoro-phenyl)-6-meth...)
Affinity DataIC50: 0.820nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed