BDBM50001781 1-(2-{4-[1-(2-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL357186

SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3F)c3cc(C)ccc23)C1=O

InChI Key InChIKey=YVFUGTZUCVMFPR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001781   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001781(CHEMBL357186 | 1-(2-{4-[1-(2-Fluoro-phenyl)-6-meth...)
Affinity DataIC50: 730nMAssay Description:Compound was tested for the displacement of [3H]spiperone from Dopamine receptor D2 from rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001781(CHEMBL357186 | 1-(2-{4-[1-(2-Fluoro-phenyl)-6-meth...)
Affinity DataIC50: 370nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001781(CHEMBL357186 | 1-(2-{4-[1-(2-Fluoro-phenyl)-6-meth...)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed