BDBM50001780 1-(2-{4-[1-(4-Chloro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL144165

SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(Cl)cc3)c3cc(C)ccc23)C1=O

InChI Key InChIKey=QMJKMWYSEUGRLA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001780   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001780(CHEMBL144165 | 1-(2-{4-[1-(4-Chloro-phenyl)-6-meth...)
Affinity DataIC50: 620nMAssay Description:Compound was tested for the displacement of [3H]spiperone from Dopamine receptor D2 from rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001780(CHEMBL144165 | 1-(2-{4-[1-(4-Chloro-phenyl)-6-meth...)
Affinity DataIC50: 450nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001780(CHEMBL144165 | 1-(2-{4-[1-(4-Chloro-phenyl)-6-meth...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed