BDBM50001270 2-(2-(quinolin-2-yl)vinyl)phenol::2-(2-Quinolin-2-yl-vinyl)-phenol::CHEMBL127545

SMILES Oc1ccccc1\C=C\c1ccc2ccccc2n1

InChI Key InChIKey=NXNDEWNGCMCWMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001270   

TargetCysteinyl leukotriene receptor 1/2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50001270(CHEMBL127545 | 2-(2-(quinolin-2-yl)vinyl)phenol | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50001270(CHEMBL127545 | 2-(2-(quinolin-2-yl)vinyl)phenol | ...)
Affinity DataIC50: 6.42E+3nMAssay Description:Reduction of recombinant ECE2 activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeprilysin(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50001270(CHEMBL127545 | 2-(2-(quinolin-2-yl)vinyl)phenol | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NeprilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed