BDBM50001263 5,7-Dichloro-4-hydroxy-3-(4-hydroxy-phenyl)-1H-quinolin-2-one::CHEMBL114610

SMILES Oc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O

InChI Key InChIKey=CBQHDIDBKFOQCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001263   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50001263(CHEMBL114610 | 5,7-Dichloro-4-hydroxy-3-(4-hydroxy...)
Affinity DataIC50: 13nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001263(CHEMBL114610 | 5,7-Dichloro-4-hydroxy-3-(4-hydroxy...)
Affinity DataIC50: 2.10E+3nMAssay Description:Compound was evaluated for in vitro inhibition of spinal cord at NMDA receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed