BDBM50001221 3-[2-(2-Acetylamino-3-naphthalen-2-yl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL315047

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=JSGRPPGXQMIRRM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50001221   

TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001221(CHEMBL315047 | 3-[2-(2-Acetylamino-3-naphthalen-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001221(CHEMBL315047 | 3-[2-(2-Acetylamino-3-naphthalen-2-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Effective concentration against Endothelin B receptor from rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001221(CHEMBL315047 | 3-[2-(2-Acetylamino-3-naphthalen-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ET-1 binding to Endothelin A receptor in cultured rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001221(CHEMBL315047 | 3-[2-(2-Acetylamino-3-naphthalen-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ET-1 binding to Endothelin B receptor in cultured rat cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B/1 receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001221(CHEMBL315047 | 3-[2-(2-Acetylamino-3-naphthalen-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against Endothelin receptor from rat heart ventricleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed