BDBM50000923 Acetic acid 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyl ester::CHEMBL92158

SMILES CC(=O)OCCCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key InChIKey=XVSYNPSLGKTSJP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000923   

TargetP2Y purinoceptor 12(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000923(CHEMBL92158 | Acetic acid 4-(2-oxo-2,3-dihydro-1H-...)
Affinity DataEC50:  950nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000923(CHEMBL92158 | Acetic acid 4-(2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed