BDBM50000913 7-(2,3-Dihydroxy-propoxy)-1,3-dihydro-imidazo[4,5-b]quinolin-2-one(HCl)::CHEMBL314763

SMILES OCC(O)COc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key InChIKey=WEBZYVCZQWRSBX-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000913   

TargetP2Y purinoceptor 12(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000913(CHEMBL314763 | 7-(2,3-Dihydroxy-propoxy)-1,3-dihyd...)
Affinity DataEC50:  260nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000913(CHEMBL314763 | 7-(2,3-Dihydroxy-propoxy)-1,3-dihyd...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000913(CHEMBL314763 | 7-(2,3-Dihydroxy-propoxy)-1,3-dihyd...)
Affinity DataEC50:  260nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed