BDBM50000844 5-[3-(4-Methoxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-1-methyl-1H-quinolin-2-one::CHEMBL415275

SMILES COC1(CCOCC1)c1cccc(OCc2cccc3n(C)c(=O)ccc23)c1

InChI Key InChIKey=SDEATAUKIMBNRR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000844   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000844(CHEMBL415275 | 5-[3-(4-Methoxy-tetrahydro-pyran-4-...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed