BDBM50000690 10,25-dimethoxy-15,15,30-trimethyl-(1S,16R)-7,23-dioxa-15,30-diazoniaheptacyclo[22.6.2.23,6.112,16.118,22.08,36.027,31]hexatriaconta-3,5,8,10,12(36),18,20,22(35),24(32),25,27(31),33-dodecaene-9,21-diol,dichloride(tubocurarine)::CHEMBL501646::Tubocurarine::Tubocurarine dichloride::Tubocurarine,d

SMILES C[N@H+]1CCc2cc(c3cc2[C@@H]1Cc4ccc(cc4)Oc5c6c(cc(c5O)OC)CC[N+]([C@@H]6Cc7ccc(c(c7)O3)O)(C)C)OC

InChI Key InChIKey=JFJZZMVDLULRGK-UHFFFAOYSA-P

Data  6 KI  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50000690   

TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50000690(Tubocurarine,d | 10,25-dimethoxy-15,15,30-trimethy...)
Affinity DataEC50:  3.20E+6nMAssay Description:In vitro ability to inhibit the binding of [125I]-alpha-bungarotoxin to nicotinic acetylcholine receptor on membranes prepared from the electric orga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Mouse)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50000690(Tubocurarine,d | 10,25-dimethoxy-15,15,30-trimethy...)
Affinity DataKi:  8.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50000690(Tubocurarine,d | 10,25-dimethoxy-15,15,30-trimethy...)
Affinity DataKi:  282nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50000690(Tubocurarine,d | 10,25-dimethoxy-15,15,30-trimethy...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
LigandPNGBDBM50000690(Tubocurarine,d | 10,25-dimethoxy-15,15,30-trimethy...)
Affinity DataKi:  6.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2011
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50000690(Tubocurarine,d | 10,25-dimethoxy-15,15,30-trimethy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2011
Entry Details
PubMed
LigandPNGBDBM50000690(Tubocurarine,d | 10,25-dimethoxy-15,15,30-trimethy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2011
Entry Details Article
PubMed