BDBM50000656 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(2-fluoro-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL38578

SMILES CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2F)C(=O)N[C@@H]1C(O)=O

InChI Key InChIKey=ZIGFHLXHJJNVOW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000656   

TargetDelta-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000656(CHEMBL38578 | 10-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  3.30nMAssay Description:Compound was tested for the inhibition of [3H]- [D-Pen2, D-Pen5]-enkephalin (DPDPE) binding to Opioid receptor delta 1 in guinea pig brain homogenate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000656(CHEMBL38578 | 10-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  92nMAssay Description:Compound was tested for the inhibition of [3H]- [D-Ala2, N-MePhe4, Gly5-ol]-enkephalin (DAMGO) binding to opioid receptor mu in guinea pig brain homo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50000656(CHEMBL38578 | 10-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for the inhibition of [3H]- (U69,593) binding to opioid receptor kappa in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed