BDBM50000439 5-Butyl-pyridine-2-carboxylic acid::5-Butyl-pyridine-2-carboxylic acid (fusaric acid)::CHEMBL24510

SMILES CCCCc1ccc(nc1)C(=O)O

InChI Key InChIKey=DGMPVYSXXIOGJY-UHFFFAOYSA-N

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50000439   

TargetTransmembrane prolyl 4-hydroxylase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 0.4-1.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataIC50: 50nMAssay Description:Inhibition of bovine adrenal medulla DBH incubated for 25 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataKi:  149nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Bovine)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50000439(CHEMBL24510 | 5-Butyl-pyridine-2-carboxylic acid |...)
Affinity DataKi:  149nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed