BDBM50000286 2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl-1,4-dithia-8-aza-spiro[4.5]dec-8-yl)-ethanone::CHEMBL149668

SMILES Clc1ccc(CC(=O)N2CCC3(CC2CN2CCCC2)SCCS3)cc1Cl

InChI Key InChIKey=SGEUQNMYMXIUJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000286   

TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000286(CHEMBL149668 | 2-(3,4-Dichloro-phenyl)-1-(7-pyrrol...)
Affinity DataIC50: 5nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed