BDBM50000278 2-(3,4-Dichloro-phenyl)-1-(2-piperidin-1-ylmethyl-piperidin-1-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(2-piperidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL131328

SMILES Clc1ccc(CC(=O)N2CCCCC2CN2CCCCC2)cc1Cl

InChI Key InChIKey=PZKHOISBMZGAFR-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000278   

TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000278(CHEMBL131328 | 2-(3,4-Dichloro-phenyl)-1-(2-piperi...)
Affinity DataIC50: 260nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000278(CHEMBL131328 | 2-(3,4-Dichloro-phenyl)-1-(2-piperi...)
Affinity DataKi:  0.480nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor kappa 1 subtype in guinea pig brain (minus cerebellum) using [3H]U-69593 as r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000278(CHEMBL131328 | 2-(3,4-Dichloro-phenyl)-1-(2-piperi...)
Affinity DataKi:  4.81E+3nMAssay Description:Compound was evaluated for its binding affinity against Opioid receptor mu 1 subtype in guinea pig brain (minus cerebellum) using [3H]-DAGO as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed