BDBM50000274 (1-{1-[2-(3,4-Dichloro-phenyl)-acetyl]-piperidin-2-ylmethyl}-pyrrolidin-3-ylidene)-acetic acid methyl ester::CHEMBL357297

SMILES COC(=O)\C=C1\CCN(CC2CCCCN2C(=O)Cc2ccc(Cl)c(Cl)c2)C1

InChI Key InChIKey=XVAYHCVKNSKOJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000274   

TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000274(CHEMBL357297 | (1-{1-[2-(3,4-Dichloro-phenyl)-acet...)
Affinity DataIC50: 4.70nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed