BDBM50000263 2-(3,4-Dichloro-phenyl)-1-(8-pyrrolidin-1-ylmethyl-1,4-dioxa-7-aza-spiro[4.5]dec-7-yl)-ethanone::CHEMBL358727

SMILES Clc1ccc(CC(=O)N2CC3(CC[C@H]2CN2CCCC2)OCCO3)cc1Cl

InChI Key InChIKey=NPBLSUKEFKYGMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000263   

TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000263(CHEMBL358727 | 2-(3,4-Dichloro-phenyl)-1-(8-pyrrol...)
Affinity DataIC50: 160nMAssay Description:Kappa-opioid receptor agonist potency in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed