BDBM49992 (E)-1-(2,3-dihydroindol-1-yl)-3-(2-furanyl)-2-propen-1-one::(E)-1-(2,3-dihydroindol-1-yl)-3-(furan-2-yl)prop-2-en-1-one::(E)-3-(2-furyl)-1-indolin-1-yl-prop-2-en-1-one::MLS000772191::SMR000376708::cid_779814

SMILES O=C(\C=C\c1ccco1)N1CCc2ccccc12

InChI Key InChIKey=XFJDULHCELCQOW-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 49992   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49992(SMR000376708 | MLS000772191 | (E)-1-(2,3-dihydroin...)
Affinity DataEC50:  1.04E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetProtein skinhead-1(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49992(SMR000376708 | MLS000772191 | (E)-1-(2,3-dihydroin...)
Affinity DataIC50: 8.59E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM49992(SMR000376708 | MLS000772191 | (E)-1-(2,3-dihydroin...)
Affinity DataEC50:  3.40E+4nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in Ach-induced current at -90 mV membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed