BDBM499656 US11020397, Compound Formula-(IIp)

SMILES CCSc1nc(O)c(C(=O)Nc2ccc(cc2)-c2nn[nH]n2)c(=O)[nH]1

InChI Key InChIKey=KCMFZUUGRZMYJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 499656   

TargetSolute carrier family 22 member 12(Human)
Acquist

US Patent
LigandPNGBDBM499656(US11020397, Compound Formula-(IIp))
Affinity DataIC50: 5.00E+4nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499656(US11020397, Compound Formula-(IIp))
Affinity DataIC50: 0.200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
Go to US Patent