BDBM499525 US11020395, Example 121.0::US11020395, Example 122.0

SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc([C@@H]2C[C@@H](C2)C#N)n1-c1c(OC)cccc1OC)c1ncc(Cl)cn1

InChI Key InChIKey=XKUVTDIIBWHHTD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 499525   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM499525(US11020395, Example 122.0 | US11020395, Example 12...)
Affinity DataEC50:  5.40nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
Go to US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM499525(US11020395, Example 122.0 | US11020395, Example 12...)
Affinity DataEC50:  28nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
Go to US Patent