BDBM49887 4-(4-methoxyphenyl)-N-phenyl-1,3-thiazol-2-amine::4-(4-methoxyphenyl)-N-phenyl-2-thiazolamine::MLS000679009::SMR000323397::[4-(4-methoxyphenyl)thiazol-2-yl]-phenyl-amine::cid_698943

SMILES COc1ccc(cc1)-c1csc(Nc2ccccc2)n1

InChI Key InChIKey=AKKBBBALMHJWAE-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 49887   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49887(4-(4-methoxyphenyl)-N-phenyl-2-thiazolamine | SMR0...)
Affinity DataEC50:  2.49E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
LigandPNGBDBM49887(4-(4-methoxyphenyl)-N-phenyl-2-thiazolamine | SMR0...)
Affinity DataIC50: 1.03E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM49887(4-(4-methoxyphenyl)-N-phenyl-2-thiazolamine | SMR0...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in human PMNL using arachidonic acid as substrate preincubated for 15 mins before substrate addition measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM49887(4-(4-methoxyphenyl)-N-phenyl-2-thiazolamine | SMR0...)
Affinity DataIC50: 400nMAssay Description:Inhibition of partially purified recombinant 5-lipoxygenase (unknown origin) using arachidonic acid as substrate preincubated for 15 mins before subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed