BDBM498269 US11014911, Example 94::US11718603, Example 94

SMILES COc1cc(C(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)N[C@@H](C)CC(F)(F)F)n(C)n1

InChI Key InChIKey=MMSHLCXVXFWWHK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498269   

LigandPNGBDBM498269(US11014911, Example 94 | US11718603, Example 94)
Affinity DataKi:  0.150nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent

LigandPNGBDBM498269(US11014911, Example 94 | US11718603, Example 94)
Affinity DataKi:  0.150nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent