BDBM497458 US11008304, Example 45

SMILES C[C@H](CO)n1nnnc1-c1cccc(NC(=O)c2cc(-c3ccc(s3)C3CC3)c(C)cn2)n1

InChI Key InChIKey=YXAWXASVFBSRBW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497458   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent

LigandBDBM497458(US11008304, Example 45)Copy SMILESCopy InChI

Affinity DataIC50: 5.5nMAssay Description:The ability (IC50) of compounds to inhibit ASK1 kinase activity was determined by HTRF KinEASE Assay System. ASK1 was purchased from Thermofisher (Ca...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/14/2021
Entry Details
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