BDBM497435 US11008304, Example 22

SMILES C[C@H](CO)n1nnnc1-c1cccc(NC(=O)c2cc(-c3cnn(c3)C(C)(C)C)c(C)cn2)n1

InChI Key InChIKey=IXULOXYURDMKMF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497435   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent

LigandBDBM497435(US11008304, Example 22)Copy SMILESCopy InChI

Affinity DataIC50: 5.5nMAssay Description:The ability (IC50) of compounds to inhibit ASK1 kinase activity was determined by HTRF KinEASE Assay System. ASK1 was purchased from Thermofisher (Ca...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/14/2021
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL