BDBM497364 US11739077, Example 20

SMILES COc1ncnc(C2CC2)c1-c1n[nH]c2CCN(Cc12)c1ccc(cn1)-c1nc(cn1C(C)C)C(F)(F)F

InChI Key InChIKey=FVWZUTOGWWEFRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497364   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM497364(US11739077, Example 20)
Affinity DataIC50: 525nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2023
Entry Details
Go to US Patent