BDBM497346 US11001595, Compound CB67645::US11111252, Compound CB67645

SMILES COc1cc2cnnc(Nc3cc(Cl)ccc3F)c2cc1OC

InChI Key InChIKey=UXOJOHLZHHIVOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497346   

TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM497346(US11111252, Compound CB67645 | US11001595, Compoun...)
Affinity DataIC50: 1.41E+4nMAssay Description:Table 9: Compounds 1 and 2, Section D., (see FIG. 4, bottom row, far right column) each inhibit VEGFR-2 and PDGFR-β for antiangiogenic effects a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
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TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM497346(US11111252, Compound CB67645 | US11001595, Compoun...)
Affinity DataIC50: 1.41E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent