BDBM497340 US11739077, Example 7

SMILES COc1ncnc(C2CC2)c1-c1nn(C)c2CCN(Cc12)c1ccc(cc1F)-c1nc(cn1C)C(F)(F)F

InChI Key InChIKey=MKONNCOIWHMPLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497340   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM497340(US11739077, Example 7)
Affinity DataIC50: 50nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2023
Entry Details
Go to US Patent