BDBM497095 US11001561, Compound 78a::US11001561, Compound 78c::US11001561, Compound 78d
SMILES Cc1c(nc(N)n(-c2cccc(Cl)c2Cl)c1=O)N1CCC2(CCC[C@@H]2N)CC1
InChI Key InChIKey=SGRCYQJJKFTRDL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 497095
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair