BDBM497094 US11001561, Compound 77

SMILES C[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1nc(C)n(C2CCCC(Cl)=C2Cl)c(=O)c1C

InChI Key InChIKey=IWPMVQYORAKVIO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497094   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Merck Patent

US Patent

LigandBDBM497094(US11001561, Compound 77)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/8/2021
Entry Details
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