BDBM496886 indole chloropyridinyl-ester derived, 9b

SMILES Clc1cccc(OC(=O)c2cccc3[nH]ccc23)c1

InChI Key InChIKey=KFRSWEZLSGNWBS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 496886   

TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496886(indole chloropyridinyl-ester derived, 9b)
Affinity DataIC50: 1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496886(indole chloropyridinyl-ester derived, 9b)
Affinity DataEC50:  1.00E+5nMAssay Description:VeroE6 cells and TMPRSS2-overexpressing VeroE6 (VeroE6TMPRSS2) cells were obtained from the Japanese Collection of Research Bioresources (JCRB) Cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed