BDBM496873 indole chloropyridinyl-ester derived, 7b

SMILES c1cc(cc(c1)S(=O)(=O)n2ccc3c2ccc(c3)C(=O)Oc4cc(cnc4)Cl)[N+](=O)[O-]

InChI Key InChIKey=LXKXHISGOOZAGB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 496873   

TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496873(indole chloropyridinyl-ester derived, 7b)
Affinity DataIC50: 120nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496873(indole chloropyridinyl-ester derived, 7b)
Affinity DataEC50:  6.98E+4nMAssay Description:VeroE6 cells and TMPRSS2-overexpressing VeroE6 (VeroE6TMPRSS2) cells were obtained from the Japanese Collection of Research Bioresources (JCRB) Cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed