BDBM496813 SARS-CoV-2 PLpro Inhibitor, 43::US20240166598, Example 38

SMILES CN(C)C(=O)C[C@@H](NC(=O)c1cccc(c1)N(C)C1CNC1)c1cccc2ccccc12

InChI Key InChIKey=RIWQJNBDHJLHNM-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 496813   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

LigandPNGBDBM496813(SARS-CoV-2 PLpro Inhibitor, 43 | US20240166598, Ex...)
Affinity DataKd: >1.00E+6nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 ug/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandPNGBDBM496813(SARS-CoV-2 PLpro Inhibitor, 43 | US20240166598, Ex...)
Affinity DataKd: >1.00E+6nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent