BDBM495267 (3-(1-(3-Chloro-2-fluorobenzyl)-2-oxo-1,2-dihydropyridin-4-yl)-5-morpholino-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl Dihydrogen Phosphate::US10995089, Example 402::US11708364, Example 402

SMILES OP(O)(=O)OCn1cc(-c2ccn(Cc3cccc(Cl)c3F)c(=O)c2)c2cc(cnc12)N1CCOCC1

InChI Key InChIKey=KYMZNFOWXOOXDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495267   

TargetMitogen-activated protein kinase 1(Human)
Agv Discovery

US Patent
LigandPNGBDBM495267(US10995089, Example 402 | (3-(1-(3-Chloro-2-fluoro...)
Affinity DataIC50: 150nMAssay Description:To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Human)
Agv Discovery

US Patent
LigandPNGBDBM495267(US10995089, Example 402 | (3-(1-(3-Chloro-2-fluoro...)
Affinity DataIC50: 10nMAssay Description:To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent