BDBM494828 (S)-N-(4- fluorobicyclo[4.2.0]octa- 1(6),2,4-trien-7-yl)-N'- hydroxy-4-((2-((2- hydroxyethyl)sulfonyl)ethyl)amino)- 1,2,5-oxadiazole-3- carboximidamide::US10988487, Example 224

SMILES OCCS(=O)(=O)CCNc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O

InChI Key InChIKey=CQXNTYFZDLPNMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494828   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494828(US10988487, Example 224 | (S)-N-(4- fluorobicyclo[...)
Affinity DataIC50: 48.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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